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CHAPTER 2 - EPITHELIUM
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 120 Ileum
TISSUE
Small Intestine
(monkey)
STAIN
Hematoxylin & Eosin
IMAGE SIZE
57,500 x 9,000 pixels
1.9 GB
FILE SIZE
68 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

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University of Minnesota
Department of Genetics, Cell Biology and Development
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Minneapolis, MN 55455

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MH 120 Ileum

Simple Columnar Epithelium with Goblet Cells

The surface area of the small intestine is increased by finger-like projections called

The is a single layer of cells that are taller than they are wide. Where the section was cut orthogonal to the surface of the villi, a single row of cells is seen.

This contains:

  • Surface Absorptive Cells (or enterocytes) - their apical surface has tightly packed microvilli to increase their surface area. This is known as a brush border. The dark line underneath the brush border is the terminal web in which the microvilli are anchored.
  • Goblet Cells - scattered cells that secrete mucus. The basophilic secretion granules form circular clusters near the apical surface.

The ultrastructure of these two cell types can be seen in EM 034 Small Intestine by transmission electron microscopy.

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