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CHAPTER 2 - EPITHELIUM
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 017 Stratified Epithelia
TISSUE
Skin (human)
Esophagus (human)
STAIN
Hematoxylin & Eosin
FIXATIVE
Bouin's Solution (skin)
Zenker's Formaldehyde (esophagus)
IMAGE SIZE
41,300 x 29,830 pixels
4.6 GB
FILE SIZE
244 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

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University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MH 017 Stratified Epithelia

Stratified Squamous Epithelia

A stratified squamous epithelium has multiple layers of cells. It is continuously replacing itself by division of the basal layer of cells. These cells change shaped as they move toward the surface and are eventually shed. Its name arises from the squamous appearance of the outermost layer of cells.

Stratified squamous epithelium is further classified by the presence or absence of keratin, a tough protective protein, at its apical surface.

  • - covered by a .
    • Number of cell layers in skin ranges from a few (thin skin) to many (thick skin)
    • Because skin is exposed to air, it is keratinized to protect the surface from abrasion and is lubricated by glycolipids to avoid desiccation
  • - lined by a .
    • Keratin is not necessary because it is constantly kept moist

The ultrastructure of thin skin is shown in EM 084 Thin Skin by transmission electron microscopy.

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