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CHAPTER 13 - ENDOCRINE GLANDS
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MHS 216 Adrenal
TISSUE
Adrenal Gland
STAIN
Hematoxylin & Eosin
IMAGE SIZE
18,261 x 18,229 pixels
1.2 GB
FILE SIZE
600 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
T. Clark Brelje and Robert L. Sorenson
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MHS 216 Adrenal

Adrenal Gland

This semi-thin section (~1.0 µm thick) of the adrenal gland has excellent cellular definition compared to normal sections (4 to 6 µm thick).

An adrenal gland is located on the top of each kidney.

  • Stroma
    • - enclosed by a thin layer of connective tissue.
    • - penetrate the capsule and branch into fenestrated capillaries that supply the cortex and medulla.
    • - cross-sections are seen in the capsule.
  • Parenchyma
    • - cells that synthesize and secrete steroid hormones.
      • - outer zone (15%) of glomerular-like clusters of cells that secrete aldosterone. The have a central nucleus and lipid filled ("foamy") cytoplasm.
      • - middle zone (80%) of two-cell wide vertical cords that secrete cortisol. The have a central nucleus and lipid filled ("foamy") cytoplasm.
      • - inner zone (7%) of one-cell wide anastomosing rows that secrete precursors of testosterone. The have a central nucleus and eosinophilic cytoplasm.
      • - modified postganglionic sympathetic neurons that secrete catecholamines (epinephrine or norepinephrine).
      • - infrequent sympathetic ganglion cells.
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