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CHAPTER 13 - ENDOCRINE GLANDS
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MHS 209 Thyroid-Parathyroid-Thymus
TISSUE
Thyroid
Parathyroid
Thymus
STAIN
Hematoxylin & Eosin
IMAGE SIZE
73,367 x 64,764 pixels
17.7 GB
FILE SIZE
524 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
T. Clark Brelje and Robert L. Sorenson
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MHS 209 Thyroid-Parathyroid-Thymus

Thyroid-Parathyroid-Thymus

This specimen is unusual in that a parathyroid gland is embedded within the thyroid which itself is fused with the thymus. This occurs when parts of each tissue fail to migrate to their proper locations during development.

    • - spherical follicles in which thyroid hormones are stored.
      • - lumen of each follicle is filled with the gel-like mass called colloid. It is mostly the protein thyroglobulin (pink) and bound thyroid hormones.
      • - follicles are lined by a simple cuboidal to columnar epithelium depending on functional activity. Secrete thyroid hormones when active.
    • Parafollicular Cells (,)- small numbers of larger cells located at the periphery of follicles that secrete calcitonin.
  • - is composed of only chief cells in juveniles. Oxyphils appear after the first decade of life.
    • - comprise the majority of cells in the parathyroid and secrete parathyroid hormone (PTH).
      • Small cells (5 to 8 µm diameter) with dark nuclei and lightly stained cytoplasm.
    • - only a single cluster of cells is seen. They are larger cells (8 to 12 µm diameter) with dark nuclei and distinctly eosinophilic cytoplasm because of numerous mitochondria.
  • - composed of a large number of tightly-packed lymphocytes
© 2005-2026. T. Clark Brelje and Robert L. Sorenson