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CHAPTER 11 - SKIN
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 090 Thin Skin
TISSUE
Thin Skin
(human)
STAIN
Hematoxylin & Eosin
IMAGE SIZE
60,140 x 19,799 pixels
4.4 GB
FILE SIZE
140 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

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University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MH 090 Thin Skin

Thin Skin

Thin skin (1 to 2 mm) covers most of the body, whereas thick skin is restricted to the palms of the hands and soles of the feet.

The keratin layers often become dislodged during preparation of thin skin. In the natural state, the keratin layers would be attached to the underlying layers. The thickness of the stratum corneum is less than the cellular layers.

  • - stratified squamous keratinized epithelium divided into four strata (or layers).
    • - single layer of germinal cells resting on the basement membrane which is attached to the dermis.
    • - keratinocytes attached to each other by desmosomes on spiny processes.
    • - keratinocytes with numerous basophilic granules in their cytoplasm.
    • - thin layer of dead cells devoid of nuclei and organelles.
  • - dense irregular connective tissue that supports the epidermis.
    • - less prominent than in thick skin. They increase adhesion between the epidermis and dermis.
    • - coiled tubular glands (lightly stained) and ducts (dark stained) with simple or stratified cuboidal epithelium.
    • - thin skin has hair follicles.
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